Pathway Browser is a graphic tool to view the ubiquitination pathways of a particular E3.

HOW TO ACCESS

After searching for E3 entries through Quick Search or Advanced Search, you can see results as shown below. You can access Pathway Browser by clicking the icon .

For example, you can browse the ubiqutination pathways for 'MDM2_HUMAN', as shown below.
Try browsing MDM2_HUMAN

USAGE: You can see the ubiquitination pathway from E1 to E2, E3, and the target protein. You can control the distance of protein interactions in pathways by the "Zoom In" Zoom In or "Zoom Out" Zoom Out buttons. The "Zoom In" button enables you to see more detailed protein interactions, and the "Zoom Out" button to see less detailed ones. In Pathway Browser, rectangles and their connections indicate proteins and ubiquitinating relations, respectively. The color of a rectangle indicates E1, E2, E3, and the target protein, as follows.

  E1
  E2
  E3
  Target Protein

You can click any protein rectangle to view a ubiquitination pathway. For each rectangle, you can browse protein information by clicking the blue-colored or red-colored little boxes on the rightmost side of the protein rectangle. The blue-colored little box is linked to the corresponding entry in UniProt, and the red-colored little box to the entry in E3DB.

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